differential-tad-analysis

This skill performs differential topologically associating domain (TAD) analysis using HiCExplorer's hicDifferentialTAD tool. It compares Hi-C contact matrices between two conditions based on existing TAD definitions to identify significantly altered chromatin domains.

$ Installer

git clone https://github.com/BIsnake2001/ChromSkills /tmp/ChromSkills && cp -r /tmp/ChromSkills/20_toolBased.differential-tad-analysis ~/.claude/skills/ChromSkills

// tip: Run this command in your terminal to install the skill