differential-methylation

This skill performs differential DNA methylation analysis (DMRs and DMCs) between experimental conditions using WGBS methylation tracks (BED/BedGraph). It standardizes input files into per-sample four-column Metilene tables, constructs a merged methylation matrix, runs Metilene for DMR detection, filters the results, and generates quick visualizations.

$ インストール

git clone https://github.com/BIsnake2001/ChromSkills /tmp/ChromSkills && cp -r /tmp/ChromSkills/21.differential-methylation ~/.claude/skills/ChromSkills

// tip: Run this command in your terminal to install the skill